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| Establishment of chronic animal model of the nerve root cervical spondylosis |
| Hits 1930 Download times 1468 Received:April 20, 2015 |
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| DOI
10.11656/j.issn.1672-1519.2015.09.13 |
| Key Words
nerve root cervical spondylosis;chronic stage;animal model |
| Author Name | Affiliation | | JIN Zhe-feng | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | XU Fan-ping | Beijing Hospital of Traditional Chinese Medicine, Beijing 100010, China | | ZHU Li-guo | Wangjing Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100102, China | | YU Jie | Wangjing Hospital, Chinese Academy of Chinese Medical Sciences, Beijing 100102, China | | WANG Ping | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | BI Fang-shan | Beijing Fengsheng Special Hospital of Traditional Medical Traumatology and Orthopaedics, Beijing 100033, China |
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| Abstract
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| [Objective] To establish chronic stage model of the nerve root cervical spondylosis in the rat through simulation of chronic cervical intervertebral disc and zygapophyseal joints degeneration. [Methods] The 48 SD rats were randomly divided into two groups, model group and false operation group, and observation of intervertebral disc degeneration by cervical spine lateral X-ray respectively 1 d of preoperative and 29 d of postoperative, and detecting the right brachial plexus nerve sensory nerve and motor nerve conduction velocity, recording electrophysiological changes. [Results] The model could obviously change of intervertebral disc and nerve conduction function damage changes. [Conclusion] The method of simulation of chronic cervical intervertebral disc and zygapophyseal joints degeneration could reflect a chronic stage model of the nerve root cervical spondylosis. |
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