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Research of the distribution law of traditional Chinese medicine syndromes in patients of retreatment pulmonary tuberculosis with smear-positive
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DOI   10.11656/j.issn.1672-1519.2016.02.06
Key Words   smear positive pulmonary tuberculosis;symptoms distribution;clustering analysis
Author NameAffiliationE-mail
Zhang Dong Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300073, China
Tianjin Haihe Hospital, Tianjin Institute of Respiratory Diseases, Traditional Chinese Medicine Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin 300350, China 
 
Sun Xin Tianjin Haihe Hospital, Tianjin Institute of Respiratory Diseases, Traditional Chinese Medicine Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin 300350, China 13302031999@126.com 
Liu En-shun The Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China  
Zheng Li The Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China  
Du Zhong-zhen Tianjin Haihe Hospital, Tianjin Institute of Respiratory Diseases, Traditional Chinese Medicine Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin 300350, China  
Xie Yi Tianjin Haihe Hospital, Tianjin Institute of Respiratory Diseases, Traditional Chinese Medicine Key Research Laboratory for Infectious Disease Prevention for State Administration of Traditional Chinese Medicine, Tianjin 300350, China  
Abstract
    [Objective] Investigation on the distribution of traditional Chinese medicine(TCM) syndrome types of retreatment on smear positive pulmonary tuberculosis. [Methods] This is a multi center, large sample clinical research. To collected the common symptoms of TCM, physical signs, tongue and pulse examination from the 362 patients of retreatment smear positive pulmonary tuberculosis. Epidata3.02 software was used to build the database of TCM syndrome, SPSS 13.0 software for descriptive analysis and clustering analysis. [Results] According to the frequency of TCM syndrome, the most common was Yin-deficiency(305 cases, 84.25%), the second was Qi-deficiency(212 cases, 58.56%), next was fire-heat syndrome(166 cases, 45.86%), the fourth was blood-stasis(133 cases, 36.74%). The most common target of TCM syndrome were lung, spleen and kidney. The most common combination of syndrome factor was the second, third and the fourth TCM syndrome. The clustering analysis showed that the Qi-deficiency and the Yang-deficiency were copolymerized as the same category, the fire-heat syndrome, blood-stasis and phlegm-turbid were copolymerized as the another category. [Conclusion] The retreatment on smear positive pulmonary tuberculosis was not only characterised by "fire excess from Yin-deficiency" but also increased ratio of TCM syndrome combination of spleen and kidney. Some patients showed obvious blood-stasis syndrome.

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