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| Study to evaluate effficacy, intervention-level of acupuncture therapy based on Meta-analysis of ordinal data: major depressive disorder |
| Hits 1630 Download times 1698 Received:September 28, 2015 |
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| DOI
10.11656/j.issn.1672-1519.2016.03.03 |
| Key Words
acupuncture;major depressive disorder;ordinal data;Meta-analysis;efficacy;intervention-level |
| Author Name | Affiliation | | LI Bo | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | DU Yuan-hao | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | LIU Qiang | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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| Abstract
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| [Objective] Based on high quality data clinical evidence and Meta-analysis of ordinal data model to evaluate the efficacy, intervention-level of acupuncture treatment of major depressive disorder(MD-D). [Methods] The published papers on clinical trails for acupuncture treatment of MD-D were widely retrieved from Chinese and abroad Database. Quality of clinical evidence was evaluated by Jadad scale. Using the maximum likelihood method to fit the cumulative odds model, STATA12.0 software was used for data analyses. [Results] The 13 studies accord with the inclusive criterion were retrieved. Meta-analyses of ordinal data showed acupuncture compare with SSRIs increase the possibility of efficacy an increase of more than one level of 55%; acupuncture with SSRIs increase the possibility of efficacy an increase of more than one level of 183%. [Conclusion] According to the present stage clinical evidences, treatment mild and moderate MD-D acupuncture can be used as the main treatment method, with antidepressants can significantly improve the overall efficacy. |
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