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| A functional magnetic resonance imaging (fMRI) study on the effect of acupuncture at GB34 (Yanglingquan) on sensorimotor network in stroke patients with hemiplegia |
| Hits 2011 Download times 1649 Received:December 24, 2015 |
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| DOI
10.11656/j.issn.1672-1519.2016.05.02 |
| Key Words
stroke;hemiplegia;acupuncture;Yanglingquan;sensorimotor network;fMRI |
| Author Name | Affiliation | E-mail | | FU Cai-hong | No. 1 Area of Encephalopathy Department, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | LI Kuang-shi | No. 1 Area of Encephalopathy Department, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | | | ZOU Yi-huai | No. 1 Area of Encephalopathy Department, Dongzhimen Hospital, Beijing University of Chinese Medicine, Beijing 100700, China | zouyihuai2004@163.com |
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| Abstract
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| [Objective] To observe the characteristic of brain functional regions of the effect of acupuncture at Yanglingquan (GB34) on sensorimotor network of stroke patients with hemiplegia, and investigate the effect mechanism of acupuncture at Yanglingquan (GB34) on promoting brain reorganization of stroke patients with hemiplegia. [Methods] 12 stroke patients with hemiplegia and 8 healthy controls in accordance with the inclusive criteria were recruited and underwent resting state fMRI scanning before and after acupuncture stimulation, the method of generalized linear models was used to analyze the components of sensorimotor network extracted from all the subjects and compare the brain regions activated by acupuncturing at Yanglingquan (GB34). [Results] Compared with healthy controls, acupuncture at Yanglingquan (GB34) showed positive effect at right cingulate gyrus, right superior frontal gyrus, right medial frontal gyrus, right lingual gyrus, right declive, left precuneus and left superior parietal lobule, while negative effect mainly occurred at left anterior cingulate gyrus, left superior frontal gyrus, right superior frontal gyrus, left middle frontal gyrus, left inferior frontal gyrus, left medial frontal gyrus, right medial frontal gyrus, left superior temporal gyrus, left cuneus, and left precuneus. [Conclusion] Acupuncture at Yanglingquan (GB34) may promote the brain reorganization of stroke patients with hemiplegia by modulating some brain regions activity related to the sensorimotor network of the bilateral cerebral hemisphere and enhancing the effect of sensory feedback on motion output. |
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