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| Xuefu Zhuyu prescription for the treatment of angina pectoris: a Meta-analysis of randomized controlled trials |
| Hits 1700 Download times 1543 Received:December 25, 2015 |
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| DOI
10.11656/j.issn.1672-1519.2016.05.05 |
| Key Words
Xuefu Zhuyu prescription;coronary heart disease angina pectoris;Meta-analysis;randomized controlled trial |
| Author Name | Affiliation | E-mail | | GAO Shu-ming | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | YAO Lu | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LI Pei-chun | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | YANG Shuai | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LI Lin | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | GAO Shan | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | bianjibugs@163.com | | YU Chun-quan | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | ycq-4@163.com |
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| Abstract
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| [Objective] To quantitative evaluate the clinical effects of coronary heart disease with angina pectoris by Xuefu Zhuyu prescription. [Methods] Retrieving total 8 databases, such as Cochrane Library, Pubmed, Web of Science, Elsevier, CNKI, Wanfang, CBM, and VIP, the literatures as of December 2015 were published in both English and Chinese, which were absorbed into angina pectoris clinical randomized controlled trials that the treatment of Xuefu Zhuyu prescription alone or merged with conventional Western medicine, and compared with the treatment of conventional Western medicine. All reports which were selected in accordance with strict inclusion criteria would be analyzed with Revman 5.3 software for statistical analysis, end effect index to relative risk (RR) and 95% confidence interval (CI). [Results] A total of 10 articles were 745 cases of patients with angina pectoris included in the standard. The result showed that the treatment group effect was better than the control group (P<0.000 01; RR=1.27; 95%CI=[1.19, 1.37]). No serious adverse reactions of Xuefu Zhuyu prescription had been reported. [Conclusion] Application in the treatment of angina pectoris, Xuefu Zhuyu prescription could improve the efficiency, and had the characteristics of less adverse reaction. However, due to effect of the low quality of the absorbed studies of samples, publication bias and other factors, there has to be more high-quality, multiple-center, large-sample randomized controlled trials to validate the curative effect of Xuefu Zhuyu prescription. |
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