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| Evaluation on the therapeutic effect of Sini powder and Tongxieyao prescription and Western medicine on irritable bowel syndrome |
| Hits 1804 Download times 1650 Received:December 18, 2015 |
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| DOI
10.11656/j.issn.1672-1519.2016.05.06 |
| Key Words
Sini powder and Tongxieyao prescription;randomized controlled trial;methodology;quality evaluation |
| Author Name | Affiliation | | YAO Peng | Department of Spleen and Stomach, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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| Abstract
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| [Objective] To evaluate on the therapeutic effect of Sini powder and Tongxieyao prescription and Western medicine on irritable bowel syndrome of randomized controlled trials. [Methods] By computer retrieval CNKI (2005-2015), VIP (2005-2015) and WF (2005-2015), supplemented by manual retrieval of Tianjin University of Chinese medicine library item database. Comprehensive collection of randomized controlled trials about Sini powder and Tongxieyao prescription, to extract information and according to the Cochrane Reviewer faced 5.0 quality assessment, statistical analysis by RevMan 5.2 software. [Results] 12 clinical randomized controlled trials were included, total 1 778 patients. Meta analysis showed: the clinical total effective rate: combined effects of RR=1.30, 95%CI (1.14, 1.48), merge effect quantity inspection, Z=3.95, P<0.000 01. [Conclusion] It has significant advantage of Sini powder and Tongxieyao prescription and Western medicine in the treatment of irritable bowel syndrome in clinical total effective rate. But, all of the above indexes, most directly using simple comparison of the total effective rate, and lack of symptoms integral evaluation, therefore, in improvement the symptoms of irritable bowel syndrome, such as abdominal pain, diarrhea, defecation urgency, body tired, anorexia, etc., it is not comprehensive, systematic, intuitive reflected of the advantage of comparison Sini powder and Tongxieyao prescription and Western medicine. Because the quality of included literature is not high, the above conclusion still needs more high-quality randomized, double-blind, placebo-controlled experiment to verify. |
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