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| Isolation and structural identification of the quinate esters from the stems of Chrysanthemum morifolium Ramat. Qiju |
| Hits 1697 Download times 1276 Received:January 20, 2016 |
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| DOI
10.11656/j.issn.1672-1519.2016.08.13 |
| Key Words
Chrysanthemum morifolium Ramat. Qiju;stem;chemical constituent;structural identification |
| Author Name | Affiliation | E-mail | | QU Lu | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | SHI Wen-zhong | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | ZHANG Jing-hui | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | CHEN Kai-yan | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | WANG Tao | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | | | ZHANG Yi | Key Laboratory of Traditional Chinese Medicinal Chemistry and Analytical Chemistry of Tianjin, Tianjin 300193, China | zhwwxzh@263.net |
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| Abstract
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| [Objective] To expand the application range of genus Chrysanthemum, improve the regeneration ability and internal quality of existing resources of medicinal plants, we studied the chemical constituents of stems from Chrysanthemum morifolium Ramat. Qiju's 70% EtOH extracts. [Methods] The chemical compounds were isolated through Sephadex LH-20, ODS, Silica gel column chromatorgraphies and PHPLC chromatorgraphy and identified by chemical and spectral analysis. [Results] Eight quinate esters were obtained, and identified as 3-O-caffeoylquinic acid (1), chlorogenic acid methyl ester (2), 4-O-caffeoylquinic acid (3), 1,5-di-O-caffeoylquinic acid (4), 1,4-di-O-caffeoylquinic acid (5), methyl 3,5-di-O-caffeoylquinate (6), 3,4-di-O-caffeoylquinic acid (7), methyl 3,4-di-O-caffeoylquinate (8), respectively. [Conclusion] Compound 2 is isolated from the plant for the first time, and 3, 5, 6, 8 were obtained from stems firstly. |
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