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| Study on synergistic antioxidant activities of Liriodendrin and Glabridin |
| Hits 1801 Download times 1436 Received:May 12, 2016 |
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| DOI
10.11656/j.issn.1672-1519.2016.10.12 |
| Key Words
Liriodendrin;Glabridin;synergistic effect;antioxidant activity |
| Author Name | Affiliation | E-mail | | FENG Qian-ru | Pharmaceutical Department of Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China | | | YE Liu-qing | School of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LIU Yuan-yuan | School of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | GONG You-ming | Pharmaceutical Department of Guangdong Provincial Hospital of Traditional Chinese Medicine, Guangzhou 510120, China | | | LI Hong-yan | College of Pharmacy, Nankai University, Tianjin 300071, China | | | WANG Yan | School of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | paozhijiaoxue@126.com |
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| Abstract
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| [Objective] To evaluate the synergistic antioxidant activities of Liriodendrin and Glabridin. [Methods] The DPPH and ABTS radicals scavenging assay were established to detect the synergistic antioxidant activities of components. Isobologram method was also established to study the synergistic result. [Results] There was a synergistic antioxidant effect between Liriodendrin and Glabridin in DPPH radicals scavenging assay when the mass ratio was 3:1, addictive effect when the mass ratio was 1:1 and antagonistic effect when the mass ratio was 1:3. There was a synergistic antioxidant effect between Liriodendrin and Glabridin in ABTS radicals scavenging assay when the mass ratio was 3:1, 1:1 and 1:3. And the synergistic antioxidant effect was 1:3> 1:1> 3:1. [Conclusion] There was a synergistic antioxidant effect between Liriodendrin and Glabridin according to a certain proportion of compound. |
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