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Function of clinical pharmacy interventions on secondary prevention of myocardial infarction
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DOI   10.11656/j.issn.1672-1519.2016.11.05
Key Words   myocardial infarction;secondary prevention;pharmacy intervention;medication adherence
Author NameAffiliationE-mail
GAN Jing-shan Pharmacology Department, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China  
XU Ya-jie Pharmacology Department, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China  
YUN Nai-ru Pharmacology Department, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China yunpht@163.com 
LIU Xiu-shu Pharmacology Department, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China  
LI Ou Pharmacology Department, The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China  
Abstract
    [Objective] To explore the influence of clinical pharmacy interventions on secondary prevention of myocardial infarction.[Methods] Two hundred patients diagnosed as myocardial infarction were enrolled in this study, and these patients were randomly divided into intervention group and control group. All of the patients received conventional treatment, while the patients in the intervention group received clinical pharmacy intervention provided by pharmacists. The medication adherence and the adherence rate was recorded after intervened 1, 3, 6, 9, 12 months and the recurrence rate of myocardial infarction, hospitalization rate, and mortality were recorded after intervened 1 year.[Results] Compared with the control group, the medication adherence of the intervention group increased significantly since 3 months after intervened (P<0.05), while the adherence rate of the intervention group was decreased significantly since 3 months after intervened (P<0.05). The recurrence rate of myocardial infarction and the hospitalization rate of the intervention group decreased significantly (P<0.05), but mortality of the intervention group has no statistically significance compared with the control group (P>0.05).[Conclusion] Clinical pharmacy interventions could improve the medication adherence of the secondary prevention of the patient with myocardial infarction, decrease the adherence rate of the patients, and reduce the recurrence rate the hospitalization rate of myocardial infarction.

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