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| Differential targets and networks for vasorelaxation by active components of Radix Salviae Miltiorrhizae |
| Hits 1943 Download times 1815 Received:July 28, 2016 |
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| DOI
10.11656/j.issn.1672-1519.2016.12.01 |
| Key Words
Salviae Miltiorrhizae Radix;vasodilation;ingenuity pathway analysis;drug target |
| Author Name | Affiliation | E-mail | | ZHANG Qi | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin International Joint Academy of Biotechnology & Medicine, Tianjin 300457, China | | | WANG Miao | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin International Joint Academy of Biotechnology & Medicine, Tianjin 300457, China | | | FAN Guan-wei | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | ZHU Yan | Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin Key Laboratory of Chinese Medicine Pharmacology, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin International Joint Academy of Biotechnology & Medicine, Tianjin 300457, China | yanzhu.harvard@gmail.com |
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| Abstract
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| Salviae Miltiorrhizae Radix (SMR) is a common Chinese materia medica,which has been widely used in the treatment of cardiovascular diseases in China and East Asia.We collected literatures published in recent decade on vasodilator effects by SMR and its active components.Using IPA pathway analysis software,we further analyzed their interaction targets at cellular and molecular level,in order to illustrate the status and prospects on vasoactive research of SMR. |
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