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Effect of Xuebijing injection on D-dimer and C-reactive protein in patients with pulmonary contusion
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DOI   10.11656/j.issn.1672-1519.2016.12.08
Key Words   pulmonary contusion;Xuebijing injection;C-reactive protein;D-dimer
Author NameAffiliation
CHE Yan Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang 110002, China 
XU Lin Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang 110002, China 
YAO Jian Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang 110002, China 
HE Xu Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang 110002, China 
WANG Cheng-yuan Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang 110002, China 
SHEN Chun-jian Department of Cardiothoracic Surgery, The Second Affiliated Hospital of Shenyang Medical College, Shenyang 110002, China 
Abstract
    [Objective] To explore the effect of Xuebijing injection on D-dimer and C-reactive protein (CRP) in patients with pulmonary contusion.[Methods] A total of 80 patients with pulmonary contusion were randomly divided into observation group and control group.The control group received routine comprehensive treatment.Based on the routine comprehensive treatment,the observation group was treated with Xuebijing injection,and one course of treatment was 7 days.The serum D-dimer,CRP and WBC levels were detected on 1 d,3 d and 7 d after injuries respectively,and related clinical indexes in the two groups were compared.[Results] The serum D-dimer,CRP and WBC level increased dynamically in both group,and it decreased gradually after treatment.Compared with those in control group,the differences of D-dimer,CRP and WBC levels on 3 d and 7 d after injuries were statistically significant (P<0.05).[Conclusion] Xuebijing injection helps to reduce the level of D-dimer,CRP and WBC in patients with pulmonary contusion,promotes the recovery of pulmonary contusion.

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