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| Effect of Chinese medicine compound and active ingredient to insulin resistance of musculi skeleti by PI3K/AKT pathway |
| Hits 5743 Download times 1914 Received:September 20, 2016 |
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| DOI
10.11656/j.issn.1672-1519.2017.01.17 |
| Key Words
type 2 diabetes mellitus;musculi skeleti;insulin resistance;Chinese medicine |
| Author Name | Affiliation | E-mail | | ZHANG Bi-wei | North China University of Science and Technology, Tangshan 063000, China | | | TIAN Chun-yu | North China University of Science and Technology, Tangshan 063000, China | | | LI Ji-an | North China University of Science and Technology, Tangshan 063000, China | lnzy@vip.163.com | | LA Xiao-jin | North China University of Science and Technology, Tangshan 063000, China | | | JIAO Zi-shan | North China University of Science and Technology, Tangshan 063000, China | | | XU Xue-mei | North China University of Science and Technology, Tangshan 063000, China | | | LIN Qian | North China University of Science and Technology, Tangshan 063000, China | | | WANG Chen-bin | North China University of Science and Technology, Tangshan 063000, China | |
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| Abstract
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| Type 2 diabetes mellitus (T2DM) is a kind of metabolic disease caused by polygenic inheritance. The main pathophysiological characteristics of T2DM is insulin resistance (IR), and musculi skeleti is the main part of IR. The development mechanism of musculi skeleti insulin resistance correlates to PI3K/AKT signal pathways. Clinical and experimental research shows that Chinese medicine compound and active ingredient can control IR of musculi skeleti and help to prevent and treat T2DM. Therefor, this article discussed the improvement of musculi skeleti IR with Chinese medicine compound and active ingredient by PI3K/AKT pathway. |
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