|
| The influence of Renzhu jianpi liqi grain on gastrointestinal dysfunction in gastrointestinal movement obstacle of atropine rats |
| Hits 1697 Download times 1331 Received:October 25, 2016 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2017.02.15 |
| Key Words
Renzhu Jianpi Liqi grain;gastrointestinal movement obstacle;stomach residue rate;small intestinal propulsion rate |
| Author Name | Affiliation | | WANG Jia-jia | Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China | | WU Zhen-yu | Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China | | ZHANG Sheng-sheng | Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China | | LU Xiao-fang | Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China | | ZHAO Lu-qing | Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China | | CHANG Xiong-fei | Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China |
|
| Abstract
|
| [Objective] To observe the influence of Renzhu Jianpi Liqi grain on gastrointestinal dysfunction in gastrointestinal movement obstacle of atropine rat.[Methods] The 72 SD rats in half male and half female were randomly divided into normal group, model group, Renzhu Jianpi Liqi grain in high dose group, middle dose group, low dose group and Domperidone group, each group of 12. The drug treatment group rats lavaged with corresponding dose, normal group and model group rats lavaged with physiological saline, 1 mL/100 g. Every group lasted for 5 days. Normal group rats were intraperitoneal injection of saline after 20 minutes in the last lavage, and other groups were intraperitoneal injection atropine sulfate injection(2 mg/kg), after 20 minutes detected each group rats' gastric residual rate and small intestine propulsion rate by semisolid nutrient paste lavage method.[Results] Compared with the model group rats, the gastric residual rate of renzhu Jianpi Liqi grain high, middle, low dose group and Domperidone group were significantly lower(P<0.01, P<0.05), small intestine propulsion rate increased significantly(P<0.01).[Conclusion] Renzhu Jianpi Liqi grain can improve the gastrointestinal dysfunction in rats gastrointestinal motor function. |
|
|
|
|
|
|
|
