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Recent advance and clinical application potential of blood-activating and stasis-removing Chinese medicine for diabetic peripheral artery disease
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DOI   10.11656/j.issn.1672-1519.2017.03.01
Key Words   blood-activating and stasis-removing;diabetic peripheral artery disease;clinical application
Author NameAffiliationE-mail
HE Shuang Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin International Joint Academy of Biotechnology and Medicine, Research and Development Center of Traditional Chinese Medicine, Tianjin 300457, China 
 
ZHU Yan Tianjin State Key Laboratory of Modern Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China
Tianjin International Joint Academy of Biotechnology and Medicine, Research and Development Center of Traditional Chinese Medicine, Tianjin 300457, China 
yanzhu.harvard@icloud.com 
Abstract
    Peripheral arterial disease (PAD), a form of arteriostenosis, is induced by aggravation of distal limb arteriosclerosis. It is an indicator of cardiac and cerebral artery atherosclerosis as well as a bench mark for systemic atherosclerosis. The morbidity of peripheral arterial disease in type 2 diabetic patients is significantly increased. PAD is a typical diabetic ischemic vascular disease. Increasing evidence from various experimental models has indicated that blood-activating and stasis-removing Chinese medicine may be effective for ischemic injury repair of peripheral arterial disease. Therefore, various databases were searched and basic science and clinical literatures were analyzed in this field. The comprehensive review is aimed at providing good research ideas and methods to treat diabetic peripheral artery disease by using blood-activating and stasis-removing Chinese medicine.

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