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| Observation on clinical effect and safety on early diabetic nephropathy treated with ambrette capsule combined valsartan |
| Hits 2079 Download times 1375 Received:December 12, 2016 |
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| DOI
10.11656/j.issn.1672-1519.2017.03.05 |
| Key Words
ambrette capsule;valsartan capsule;early diabetic nephropathy |
| Author Name | Affiliation | | DAI Xuan | Tianjin Nankai Hospital, Tianjin 300100, China | | YUAN Lian-fang | Tianjin Nankai Hospital, Tianjin 300100, China | | LI Yue-hong | Tianjin Nankai Hospital, Tianjin 300100, China |
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| Abstract
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| [Objective] To observe the clinical curative effect and safety of ambrette capsules combined valsartan capsules in treating early diabetic nephropathy patients.[Methods] Eighty patients with early diabetic nephropathy were selected and randomly divided into observation group and control group, 40 cases in each group. Two groups of patients were given the conventional foundation treatment. The observation group of patients were given oral ambrette capsules combined valsartan capsules treatment. Patients in control group were given valsartan capsules treatment. All groups were given drug treatment for 3 months continuously. The level of urine trace albumin excretion rate (UAER), serum urea nitrogen (BUN) and creatinine (Scr) changes between two groups of patients before and after treatment would be compared and analyzed.[Results] Compared among the UAER, BUN and Scr of observation group before and after treatment,the difference was statistically significant. Compared among the UAER, BUN, Scr of control group before and after treatment,the difference was statistically significant. The UAER of observation group is decreased more significantly than the control group(P<0.05) after treatment. The degree of decrease in BUN and Scr between two groups after treatment is not obvious (P>0.05).[Conclusion] Using ambrette capsules combined valsartan capsules treating early diabetic nephropathy, both had good synergetic effect. |
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