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Correlations between stress response neuroendocrinology and syndromes of global internal damage in Chinese medicine
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DOI   10.11656/j.issn.1672-1519.2017.03.17
Key Words   stress response;syndromes in traditional Chinese medicine;stagnation of Qi due to depression of the liver;spleen asthenia;kidney asthenia;neuroendocrine axes
Author NameAffiliation
HUANG Bing-shan America and Canada Traditional Chinese Medicine Research Associations 
HAO Ji-shun America and Canada Traditional Chinese Medicine Research Associations 
HE Yu-xin America and Canada Traditional Chinese Medicine Research Associations 
XIE Jing-ri America and Canada Traditional Chinese Medicine Research Associations 
YANG Chang-qing America and Canada Traditional Chinese Medicine Research Associations 
SHI Ling-zhi America and Canada Traditional Chinese Medicine Research Associations 
Steven Aung America and Canada Traditional Chinese Medicine Research Associations 
ZHONG Yuan America and Canada Traditional Chinese Medicine Research Associations 
WU Ben-hong America and Canada Traditional Chinese Medicine Research Associations 
LIU Jin-di America and Canada Traditional Chinese Medicine Research Associations 
LIAO Zhong-chou America and Canada Traditional Chinese Medicine Research Associations 
WANG Jian America and Canada Traditional Chinese Medicine Research Associations 
Abstract
    Syndrome-differentiation is the essence and treasure of traditional Chinese medicine, which was established by thousands of years and summarized in recent years. The syndromes appear at different stages of stress-related diseases. It is found that there are close correlations between the syndromes and the three axes of the neuroendocrine systems. The physiological functions and pathologic changes caused by the stress response in nervous, endocrine, and immune systems constitute the foundation of syndromes in traditional Chinese medicine. The physiology and pathology of the liver, spleen and kidney systems have identical manifestations with the main changes of those three axes of the neuroendocrine systems. The signs and symptoms of those three axes not only manifest changes of the liver, spleen, and kidney systems but also the heart and lung systems, as well as six Fu organs and meridians. Those three axes form the meeting area and integrating points for traditional Chinese medicine and conventional western medicine. The physiology and pathology of neuroendocrine including endocrine axes and vegetative nerve joint axe is the base of syndrome. The study revealed substantial evidence of syndromes in traditional Chinese medicine, which may influence teaching, researching, and practice among traditional Chinese medicine, conventional medicine, and integrative medicine in the future.

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