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Present research situation and thinking of drug in treating hyperuricemia |
Hits 3222 Download times 1577 Received:January 10, 2017 |
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DOI
10.11656/j.issn.1672-1519.2017.05.02 |
Key Words
hyperuricemia;uric acid production and excretion;mechanism;new drug discovery |
Author Name | Affiliation | E-mail | LIU Jin-chang | Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | WANG Tao | Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | wangtao@tjutcm.edu.cn |
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Abstract
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Hyperuricemia is a common metabolic disease in clinic with a growing tendency of morbidity. Hyperuricemia is one of the factor causes of hypertension, diabetes, cardiovascular disease and chronic renal failure, affecting life quality of patients. Generally, reducing of uric acid production and increasing of uric acid excretion are the major methods in clinic therapy. The kinds of medication are limited and not enough for clinic demand. This paper reviewed the pathogenesis mechanism research and new drug development of hyperuricemia, analyzed the characters of traditional Chinese medicines on hyperuircemia therapy, provided a thought of anti-hyperuircemia new drug research and development on the basis of clinic effective traditional Chinese medicines. |
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