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| Clinical observation on the therapeutic effect of treating central retinal vein occlusion with macular edema based on the theory of accumulation of blending of phlegm and blood stasis |
| Hits 1909 Download times 1413 Received:January 12, 2017 |
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| DOI
10.11656/j.issn.1672-1519.2017.05.06 |
| Key Words
macular edema;clinical efficacy;blending of phlegm and blood stasis |
| Author Name | Affiliation | | WANG Hui-bo | Department of Ophthalmology, Xuanwu Traditional Chinese Medicine Hospital Beijing, Beijing 100050, China | | WEI Qi-ping | Department of Ophthalmology, Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China |
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| Abstract
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| [Objective] To explore treatment protocol with higher performance-cost ratio by a clinical controlled observation on anti-VEGF and traditional Chinese medicine in the treatment of central retinal vein occlusion (CRVO) with macular edema (ME).[Methods] Fifty-four cases of CRVO with ME from Jal. 2014 to Sep. 2016 were brought into a prospective controlled research, seperated with a 1:1 ad rationem, 27 cases were treated by Chinese medicine, and the other 27 cases were treated by anti-VEGF for 2 courses (56 days). Then visual acuity and data of optical coherence tomography for ME of the two groups, before and after treatment, were analyzed statistically to evaluate the clinical effect.[Results] The clinical observation had been made on 52 patients (52eyes) in 2 groups with 26 patients (26eyes) of western medicine (anti VEGF) in one group and 26 patients (26eyes) of Chinese medicine in the other group, with one case exit in each group. Visual acuity:visual acuity of patients in both groups was increased after treatment(P<0.000 1, P<0.000 1), but there were no statistical differences between the two groups (P>0.05). Macular edema:the maximum of the macular retina thickness and the average of the macular central retina thickness of patients in both groups was reduced after treatment(P<0.001, P<0.000 1), but there were no statistical differences between the two groups (P>0.05).[Conclusion] The experienced prescription provides similar efficacy to anti-VEGF in the treatment of central retinal vein occlusion with macular edema. |
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