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| Research progress of liver toxicity mechanism in tripterygium |
| Hits 2412 Download times 1572 Received:February 15, 2017 |
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| DOI
10.11656/j.issn.1672-1519.2017.05.21 |
| Key Words
Tripterygium wilfordii Hook. f.;liver toxicity;mechanism |
| Author Name | Affiliation | E-mail | | LI Yan | Second Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | | | FU Bin | Second Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | fubin5359@126.com | | LIANG Bing-nan | Second Affiliated Hospital to Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | |
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| Abstract
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| Tripterygium wilfordii Hook. F. (TWHF) belongs to celastraceae. It is a traditional Chinese medicine with a variety of pharmacological effects, which is applied for many diseases because of its significant effects. TWHF side effects are involved in multiple organ systems, and the liver toxicity events caused by TWHF were often reported, which limits its applications in clinical. Liver toxicity of TWHF in this study is summarized on Pathology, molecular mechanism and so on, in order to provide theoretical basis for clinical application and research. |
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