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Clinical observation of “Xinnao Xuemai Ning” in the treatment of hypothyroidism
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DOI   10.11656/j.issn.1672-1519.2017.06.05
Key Words   Xinnao Xuemai Ning;hypothyroidism;clinical effect
Author NameAffiliationE-mail
REN Yong-li Department of Diabetes, Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300130, China  
REN Ming Department of Diabetes, Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300130, China renming0622@hotmail.com 
MU Jiao Department of Acupuncture, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
ZHANG Zeng-ying Department of Expert, Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine, Tianjin 300130, China  
Abstract
    [Objective] To observe the intervention effect of the “Xinnao Xuemai Ning”, ZHANG Zeng-ying's prescription in the treatment of hypothyroidism. [Methods] The patients who meet the requirements were divided into 3 groups: the “Xinnao Xuemai Ning” low dose group, high dose group and the thyroid hormone tablet control group. Forty individuals were in each group. Each group of patients were treated with drugs, to investigate the effects of different doses of “Xinnao Xuemai Ning” after 24 weeks, 48 weeks on the patient's curative effect, symptom score, TSH, FT3, FT4 valued by using the statistical analysis method. [Results] 1)After 24 and 48 weeks treatment, “Xinnao Xuemai Ning” in high and low dose groups can significantly improve the clinical efficacy, integral syndrome, can significantly decrease TSH and increase FT3, FT4 value with statistical significance. 2) “Xinnao Xuemai Ning” high and low dose groups in improving the clinical efficacy, symptom scores were better than the control group. 3) The overall effect of the high dose group was better than that of the low dose group. 4) The curative effect of “Xinnao Xuemai Ning” after 48 weeks was better than after 24 weeks. [Conclusion] Professor ZHANG Zeng-ying's prescription “Xinnao Xuemai Ning” can surely improve the curative effect for treating hypothyroidism. It is better than western medicine in the improvement of syndrome and clinical curative effect and with the longer time and dose more effective. No adverse effect on liver and renal function, medication safety.

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