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| Study on anti-ventricular arrhythmia effect induced by aconitine treated by Qibo Shengmai granules |
| Hits 1285 Download times 1236 Received:February 14, 2017 |
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| DOI
10.11656/j.issn.1672-1519.2017.08.17 |
| Key Words
Qibo Shengmai granule;aconitine;ventricular arrhythmia |
| Author Name | Affiliation | E-mail | | WANG Yan-yun | Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China | | | CHEN Wen | Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China | | | HU Yuan-hui | Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China | huiyuhui55@sohu.com | | ZHANG Wan-tong | Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China | | | SHI Shuai | Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Beijing 100053, China | |
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| Abstract
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| [Objective] To evaluate the effect of the anti-ventricular arrhythmia of Qibo Shengmai granules.[Methods] The experimental arrhythmia model in rat was caused by veins constant speed pumping aconitine. Relative index of electrocardiogram and the effect of Qibo Shengmai granules to arrhythmia was observation.[Results] Compared with model group, Qibo Shengmai granules prolonged the latent time of ventricular arrhythmia induced by aconitine in high, medium and low dose group (P<0.05, P<0.01). The high-dose group and mid-dose group also could significantly delay cardiac arrest (CA) time (P<0.05, P<0.01) and increase the dose of aconitine when CA appears (P<0.01).[Conclusion] Qibo Shengmai granules has anti-ventricular arrhythmia effect induced by aconitine. |
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