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| Effect of Fuke Guanchang Ⅱon apoptosis rate of endometrial cells |
| Hits 1239 Download times 1066 Received:March 24, 2017 |
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| DOI
10.11656/j.issn.1672-1519.2017.08.18 |
| Key Words
endometriosis;endometrial stromal cell;Fuke Guanchang Ⅱ;hypoxia |
| Author Name | Affiliation | E-mail | | HUA Dan-dan | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LI Pei-lin | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | peilin@wo.com.cn | | WANG Jian-ling | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | wjl_y@126.com | | WANG Yue-ling | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LI Jie | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | | | ZHAO Zhi-mei | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | |
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| Abstract
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| [Objective] To study the effect of hypoxia on apoptosis of endometrial cells and the intervention effect of Fuke Guanchang Ⅱ.[Methods] The apoptosis rate of the cells was detected in normal oxygen and hypoxia environment for 24 hours.[Results] The apoptosis rate of the hypoxia cells was significantly lower than that of normal endometrial cells, but it increased after the intervention of traditional Chinese medicine.[Conclusion] In the ischemic and hypoxic environment, the endometrial cells of the patients with endometriosis have strong anti apoptotic ability. The anti apoptotic ability of eutopic endometrium was weakened by intervention of traditional Chinese Medicine. |
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