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| Meta-analysis of curative effect of invigorating spleen to resolving phlegm on turbid phlegm syndrome of hyperlipidemia |
| Hits 1879 Download times 1772 Received:May 30, 2017 |
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| DOI
10.11656/j.issn.1672-1519.2017.11.05 |
| Key Words
traditional Chinese medicine;hyperlipidemia;invigorating spleen to resolving phlegm;turbid phlegm syndrome;Meta-analysis |
| Author Name | Affiliation | E-mail | | PENG Dan-hong | School of Basic Medical Science of Guangzhou University of Chinese Medicine, Guangzhou 510006, China | | | WANG Yan-ping | School of Basic Medical Science of Guangzhou University of Chinese Medicine, Guangzhou 510006, China | | | LIU Xiao-qi | School of Basic Medical Science of Guangzhou University of Chinese Medicine, Guangzhou 510006, China | | | XIE Rong | School of Basic Medical Science of Guangzhou University of Chinese Medicine, Guangzhou 510006, China | | | LI Xian-tao | School of Basic Medical Science of Guangzhou University of Chinese Medicine, Guangzhou 510006, China | lxt150@126.com |
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| Abstract
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| [Objective] To systematically review the curative effect of traditonal Chinese medicine (TCM) in patients with hyperlipidemia of turbid phlegm syndrome.[Methods] Databases such as Pubmed, VIP, Wanfang Data and CNKI were searched for the randomized controlled trails about traditional Chinese medicine as the interventions for hyperlipidemia of turbid phlegm syndrome from January 1st, 2011 to July 30th, 2016. Screening and extracting the eligible literature according to the inclusion and exclusion criteria and evaluating them by Jadad scale and Revman 5.3 software.[Results] A total of 8 studies involving 688 patients were included. The Meta-analysis showed that compared with western medicine, TCM can significantly improve the total curative effect[OR=1.9, 95%CI (1.23, 2.94), Z=2.89, P=0.004] and curative effect of TCM syndromes[OR=9.65, 95%CI(5.56, 16.73), Z=8.07, P<0.000 01] of hyperlipidemia patients of turbid phlegm syndrome, as well as decreasing the plasma level of TG[SMD=-0.02, 95%CI (-1.47, -0.16), Z=2.45, P=0.01]. But it did not show any difference on TC, LDL-C, HDL-C and adverse reactions between TCM and Western medicine (P>0.05).[Conclusion] TCM is superior than western medicine in terms of curative effect of laboratory tests,TCM syndromes and plasma level of TG, but it still needs more reliable studies to vertification. |
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