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Research advance in the relationship between the polycystic ovary syndrome and gut microbiota and the intervention effect of berberine
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DOI   10.11656/j.issn.1672-1519.2017.12.19
Key Words   polycystic ovary syndrome;insulin resistance;gut microbiota;berberine
Author NameAffiliationE-mail
WANG Ting Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
ZHAO Zhi-mei The First Affiliatted Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China zhaozhim2003@aliyun.com 
ZHOU Yao Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
HU Zu-xian Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
XIA Tian The First Affiliatted Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
YAN Ping The First Affiliatted Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
Abstract
    The pathogenesis of polycystic ovary syndrome pathophysiological basis is insulin resistance. Gut microbiota is acquired important "organ", found in human intestinal flora and affect the body's own balance. Studies suggest that the gut microbiota imbalance can cause insulin resistance, so closely linked with polycystic ovary syndrome and gut microbiota. The present study showed the gut microbiota was improved by berberine in treatment of insulin resistance and other metabolic abnormalities disease. Berberine can through the intervention of gut microbiota to treat polycystic ovary syndrome. This article reviewed the relationship between polycystic ovary syndrome and gut microbiota and berberine on gut microbiota of intervention effect in the treatment of polycystic ovary syndrome.

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