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Research advance in the relationship between the polycystic ovary syndrome and gut microbiota and the intervention effect of berberine |
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DOI
10.11656/j.issn.1672-1519.2017.12.19 |
Key Words
polycystic ovary syndrome;insulin resistance;gut microbiota;berberine |
Author Name | Affiliation | E-mail | WANG Ting | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | ZHAO Zhi-mei | The First Affiliatted Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | zhaozhim2003@aliyun.com | ZHOU Yao | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | HU Zu-xian | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | XIA Tian | The First Affiliatted Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | YAN Ping | The First Affiliatted Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | |
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Abstract
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The pathogenesis of polycystic ovary syndrome pathophysiological basis is insulin resistance. Gut microbiota is acquired important "organ", found in human intestinal flora and affect the body's own balance. Studies suggest that the gut microbiota imbalance can cause insulin resistance, so closely linked with polycystic ovary syndrome and gut microbiota. The present study showed the gut microbiota was improved by berberine in treatment of insulin resistance and other metabolic abnormalities disease. Berberine can through the intervention of gut microbiota to treat polycystic ovary syndrome. This article reviewed the relationship between polycystic ovary syndrome and gut microbiota and berberine on gut microbiota of intervention effect in the treatment of polycystic ovary syndrome. |
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