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| Clinical observation of removing turbidity and detoxication decoction combined with metformin effect on lipoprotein lipase in patients with type 2 diabetes |
| Hits 1848 Download times 1302 Received:October 16, 2017 |
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| DOI
10.11656/j.issn.1672-1519.2018.02.06 |
| Key Words
detoxication decoction;type 2 diabetes;lipoprotein lipase;turbid |
| Author Name | Affiliation | E-mail | | WANG Bin | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LIU Jie | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | WANG Yingyue | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | CAO Hongbo | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | caohongboebm@foxmail.com |
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| Abstract
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| [Objective] To observe the effect of removing turbidity and detoxication decoction combined with metformin on Lipoprotein lipase in patients with type 2 diabetes.[Methods] The 100 Patients were screened with type 2 diabetes who belong to turbidity and detoxication intrinsic type, and divided into treatment group and control group randomly. The treatment group added removing turbidity and detoxication decoction on basis of conventional treatment. Clinical symptoms and signs were evaluate, also the change of triglycerides, total cholesterol, high density lipoprotein cholesterol, low density lipoprotein cholesterol, free fatty acids, and lipoprotein lipase after 8 weeks were detected.[Results] In the course of the study, 9 cases were lost, and 91 cases were completed, of which 44 cases in the treatment group and 47 cases in the control group. The two groups showed no difference before treatment. After treatment, the clinical symptoms and signs of the treatment group were significantly improved compared with the control group, the levels of serum TG, TC, LDL, FFA were significantly decreased in the treatment group, LPL level was significantly increased, compared with the control group, the difference was statistically significant.[Conclusion] Detoxication decoction may increase the level of serum LPL to affect the lipid metabolism of patients, in order to improve the level of blood lipid in type 2 diabetic patients and relieve the clinical symptoms and signs. |
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