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| Clinical study of Naoxueshuan tablet against convalescent stroke of blood stagnation obstruction syndrome |
| Hits 1847 Download times 1238 Received:January 04, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.04.05 |
| Key Words
Naoxueshuan tablet;stroke;blood stagnation obstruction syndrome;clinical efficiency |
| Author Name | Affiliation | | GUO Jiakui | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | SUN Xigang | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300250, China | | WU Di | Tianjin Huanhu Hospital, Tianjin 300350, China | | LYU Fuquan | Tianjin Nankai Hospital, Tianjin 300100, China | | JI Xuequn | Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin 300120, China | | XIONG Jie | Affiliated Hospital of Logistics College of Chinese People's Armed Police Forces, Tianjin 300162, China |
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| Abstract
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| [Objective] To observe the clinical efficiency of Naoxueshuan tablets in treating convalescent stroke of blood stagnation obstruction syndrome. [Methods] Patients were divided into experiment group and control group with a multicentre, randomized, and controlled method, 72 cases in each group. Patients in both groups all received basic treatment, and Aspirin Enteric-coated tablets 100 mg once a day was applied to control group, while Naoxueshuan tablets 1.2 g three times a day with Aspirin Enteric-coated tablets 100 mg once a day was applied to experiment group, with a treating period of 12 weeks. NIHSS, modified Rankin, Barthel index, SS-QOL, and traditional Chinese medicine (TCM) symptom score were applied to evaluate the efficiency at 6, 12 and 24 week. [Results] All the scores were improved in both groups after treating (P<0.05). The treatment group efficiency was 90.00%, and control group efficiency was 73.44%, there was significant difference between two groups (P<0.05). NIHSS, Barthel index and TCM symptom scores were better in experiment group than that in control group at week 12 (P<0.05). NIHSS, Barthel index, SS-QOL, and TCM symptom scores were better in experiment group than that in control group at followed up to 24 week(P<0.05). Modified Rankin showed the same improvement in both groups (P>0.05). [Conclusions] Naoxueshuan tablets could significantly improve the symptoms and neural function, raise life quality of convalescent stroke of blood stagnation obstruction syndrome, with a definite curative efficiency, which should be spread and applied widely. |
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