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| Clinical observation of Yinqiao powder for regulating respiratory virus associated asthma in Th1/Th2 cytokines |
| Hits 1484 Download times 1334 Received:December 20, 2017 |
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| DOI
10.11656/j.issn.1672-1519.2018.04.08 |
| Key Words
respiratory virus associated asthma;Yinqiao powder;Th1/Th2;IFN-γ/IL-4 |
| Author Name | Affiliation | E-mail | | CHANG Li | Pneumology Department, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | ZHU Zhengang | Pneumology Department, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | 13820168940@126.com |
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| Abstract
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| [Objective] To observe the clincal effect of Yinqiao powder on treating the respiratory virus associated Asthma(RVA) and Th1/Th2 cytokines. [Methods] The 68 RVA patients were randomly divided into control group (32 cases, conventional Western medicine treatment) and treatment group (36 cases, conventional Western medicine treatment+Yinqiao powder). Two groups were treated 10 days. In prior-treatment and post-treatment, the change of the related indexes were observed, including the asthma control test (ACT score), lung function(FEV1, FEV1/FVC%, PEF), curative effect of TCM and Th1/Th2 cytokines (sIgA, IL-4, IFN-γ, IFN-γ/IL-4). [Results] After treatment, two groups of ACT score was obviously improved, the treatment group was better than that of control group (P<0.05). On the lung function improvement, the treatment group was better than the control group(P<0.05). On TCM symptoms, the treatment group effective rate was 94.44% (34/36), the control of the effective rate was 71.87% (23/32). After treatment, the treatment group sIgA levels higher than the control group (P<0.05). IFN-4 and IFN-γ/IL-4 is lower than the control group (P<0.05), IL-4 levels not seen differences between two groups (P>0.05). [Conclusion] Yinqiao Powder combined with conventional Western medicine therapy RVA clinical curative effect is superior to the conventional Western medicine therapy, this may be related to Yinqiao Powder can regulate Th1/Th2 cytokines of patients, reverse the imbalance between factors, thereby reducing the airway inflammation. |
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