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| Clinical effect of Qingfei Yishen decoction on senile pneumonia and its effect on serum CD4+ and CD8+ levels |
| Hits 2537 Download times 1265 Received:January 24, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.05.05 |
| Key Words
Qingfei Yishen decoction;senile pneumonia;immunization |
| Author Name | Affiliation | E-mail | | MENG Yong | Henan Traditional Chinese Medicine Hospital, Zhengzhou 450002, China | | | LU Xiaofan | Henan Traditional Chinese Medicine Hospital, Zhengzhou 450002, China | | | WANG Yanmei | Henan Traditional Chinese Medicine Hospital, Zhengzhou 450002, China | mywd1966@sina.com | | LI Bin | Henan Traditional Chinese Medicine Hospital, Zhengzhou 450002, China | | | GAN Dekun | Henan Traditional Chinese Medicine Hospital, Zhengzhou 450002, China | |
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| Abstract
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| [Objective] To explore the curative effect of Qingfei Yishen decoction on the senile pneumonia (heat obstruct pulmonary syndrome) and the impact on serum CD4+ and CD8+ levels.[Methods] Senile pneumonia patients were randomly divided into control group and treatment group, control group given anti-inflammatory, eliminating phlegm treatment to smooth wheezing, antifebrile; on the basis of the control treatment, the treatment group was given Qingfei Yishen decoction. Clinical curative effect was compared between the two groups before and after treatment, and follow-up 1 month, like routine blood, c-reactive protein, symptom scores, imaging, the change of serum level of CD4+, CD8+.[Results] The total effective rate was 80.00% in the control group, and the treatment group was significantly higher than the control group (96.67%, P<0.05). The scores of cough, yellow phlegm and thirst symptoms in the treatment group were significantly lower than those in the control group (P<0.05). After treatment, the leukocyte count, neutrophil ratio, c-reactive protein, and chest CT scores were significantly lower than those in the control group (P<0.05). CD4+ in the treatment group was increased in the treatment group (P<0.05, P<0.01), CD8+ in the treatment group showed a significant decrease than those in the control group (P<0.05).[Conclusion] The curative effect of Qingfei Yishen decoction of senile pneumonia (heat obstruct pulmonary syndrome) is significant, and its mechanism may be related to reducing inflammatory response and regulating immunity. |
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