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| Advances in study of the effect of traditional Chinese medicine on the intestinal tight junction proteins |
| Hits 2700 Download times 1322 Received:January 12, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.06.19 |
| Key Words
tight junction protein;mechanical barrier;traditional Chinese medicine |
| Author Name | Affiliation | E-mail | | CHANG Xiongfei | Digestion Center, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China
Beijing University of Chinese Medicine, Beijing 100029, China | | | ZHAO Luqing | Digestion Center, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China | | | JIA Mengdi | Digestion Center, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China | | | ZHU Chunyang | Digestion Center, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China | | | ZHANG Shengsheng | Digestion Center, Beijing Hospital of Traditional Chinese Medicine Affiliated to Capital Medical University, Beijing 100010, China | zhss2000@163.com |
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| Abstract
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| The intestinal mechanical barrier plays an important role in protection the body from infiltrating of toxic substances and the tight junction proteins were the structural basis, including claudin-1, occluidn and ZO-1 and so on. The intestinal mechanical barrier and tight junction proteins were closely related to many digestive diseases, such as ulcerative colitis, acute pancreatitis, irritable bowel syndrome, functional dyspepsia. Recently many researches have found that the traditional Chinese medicine can modulate the intestinal tight junction proteins. This article reviewed the advances in study of the effect of traditional Chinese medicine on the intestinal tight junction proteins. |
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