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| Clinical study of Xiaoyan decoction combined with acupuncture and moxibustion therapy on fatigue related to chemotherapy |
| Hits 1441 Download times 1202 Received:April 02, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.07.06 |
| Key Words
chemotherapy related fatigue;acupuncture therapy;cancer fatigue scale;quality of life |
| Author Name | Affiliation | E-mail | | ZHANG Lili | The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LI Wentao | The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | LI Haipeng | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | JIA Yingjie | The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | jiayingjie1616@sina.com |
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| Abstract
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| [Objective] To observe the effect of Xiaoyan decoction combined with acupuncture on the fatigue related to chemotherapy.[Methods] The 80 patients were randomly divided into treatment group (40 cases) and control group (40 cases). The two groups were treated with chemotherapy regimen according to the needs of the disease. The treatment group started oral Xiaoyan Decoction (1 doses daily, water decoction, 300 mL, 2 times and 3 weeks) from the first day of chemotherapy and combined with acupuncture and moxibustion for 3 weeks (1 times a day for a total of 3 weeks). The control group did not give other intervention measures. Before chemotherapy, seventh days of chemotherapy and twenty-first days of chemotherapy, the cancer fatigue scale (cancer fatigue scale, CFS), TCM Syndrome Evaluation and cancer treatment function evaluation Fatigue Scale (FACT-F) were used to compare the changes of fatigue, TCM syndrome score and quality of life in two groups before chemotherapy, seventh days of chemotherapy, twenty-first days of chemotherapy, and the change of quality of life. The curative effect of medical syndrome was compared.[Results] Compared with this group before chemotherapy, the seventh days of CFS in the treatment group increased (P<0.05) in the emotional dimension, body dimension and total score than before chemotherapy (P<0.05), and the CFS dimensions and total scores of the control group increased (P<0.05) before chemotherapy, and the total score of CFS was higher than that before chemotherapy (P<0.05). Compared with the seventh days of chemotherapy in this group, all the dimensions and total scores of CFS in the twenty-first day chemotherapy group decreased (P<0.05), and the emotional dimension and total score of the control group decreased (P<0.05). The dimensions and total scores of CFS in the two groups were significantly lower than those in the control group (P<0.01), and the total effective rate of TCM syndrome integral treatment group was 90% significantly better than that of the control group (P<0.01). TCM syndrome score:compared with this group before chemotherapy, the syndrome score of the treatment group for seventh day patients increased (P<0.05), twenty-first (P<0.05), twenty-first The symptom score of day syndrome was significantly lower (P<0.01), and the symptom scores of seventh days and twenty-first days in the control group increased (P<0.01). Compared with the seventh day chemotherapy group, the symptom score of twenty-first days of chemotherapy was reduced (P<0.01). The symptom scores of the two groups were lower than those in the control group (P<0.01) during the same period (P<0.01); quality of life score:before chemotherapy in this group In comparison, the scores of emotional state and functional status in the treatment group decreased seventh days after chemotherapy (P<0.05). The score of physical condition, emotional state and additional condition increased (P<0.05) on the twenty-first day, and the scores of each index in the control group decreased (P<0.05), and the score of physical condition, function and additional condition of the twenty-first day chemotherapy decreased (P<0.05), and the scores of the treatment group and the control group were all higher than that in the seventh day chemotherapy group (P<0. 05); the 2 groups were significantly higher than those in the control group (P<0.05).[Conclusion] Xiaoyan decoction combined with acupuncture and moxibustion therapy can effectively improve the chemotherapy related fatigue and improve the quality of life in patients. |
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