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Effect of panax notoginsenosides plus amiodarone on left atrial diameter and cardiac ankyrin repeat protein in patients with paroxysmal atrial fibrillation
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DOI   10.11656/j.issn.1672-1519.2018.08.04
Key Words   panax notoginsenosides;amiodarone;paroxysmal atrial fibrillation;left atrial diameter;cardiac ankyrin repeat protein
Author NameAffiliationE-mail
KUANG Rongren Shenzhen Tiaditional Chinese Medicine Hospital, Shenzhen 518033, China  
YUAN Liping Longgang Central Hospital of Guangdong Province, Shenzhen 518116, China  
HE Xianzhi The People's Hospital of Guangdong Zhuhai, Zhuhai 519000, China  
ZHANG Zhong Shenzhen Tiaditional Chinese Medicine Hospital, Shenzhen 518033, China zzicu@126.com 
Abstract
    [Objective] To discuss the effect of panax notoginsenosides (PNS) or plus amiodarone on left atrial diameter (LAD) and cardiac ankyrin repeat protein(CARP) in patients with paroxysmal atrial fibrillation(PAF).[Methods] Seventy PAF patients were randomized into PNS plus amiodarone group (35 cases) and amiodarone group (35 cases). The rate of sinus rhythm maintenance, LAD and CARP were observed within 6 months of follow-up.[Results] It's demonstrated that the rate of sinus rhythm maintenance in PNS plus amiodarone group was significantly higher than that in amiodarone group (P<0.05). LAD in PNS plus amiodarone group was significantly lower than that in amiodarone group (P<0.05). CRAP in PNS plus amiodarone group was significantly lower than that in amiodarone group (P<0.05).[Conclusion] Compared to amiodarone alone, PNS plus amiodarone can significantly reduce AF recurrence, LAD and CARP in PAF patients.

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