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Effect of panax notoginsenosides plus amiodarone on left atrial diameter and cardiac ankyrin repeat protein in patients with paroxysmal atrial fibrillation |
Hits 1379 Download times 1356 Received:June 26, 2017 |
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DOI
10.11656/j.issn.1672-1519.2018.08.04 |
Key Words
panax notoginsenosides;amiodarone;paroxysmal atrial fibrillation;left atrial diameter;cardiac ankyrin repeat protein |
Author Name | Affiliation | E-mail | KUANG Rongren | Shenzhen Tiaditional Chinese Medicine Hospital, Shenzhen 518033, China | | YUAN Liping | Longgang Central Hospital of Guangdong Province, Shenzhen 518116, China | | HE Xianzhi | The People's Hospital of Guangdong Zhuhai, Zhuhai 519000, China | | ZHANG Zhong | Shenzhen Tiaditional Chinese Medicine Hospital, Shenzhen 518033, China | zzicu@126.com |
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Abstract
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[Objective] To discuss the effect of panax notoginsenosides (PNS) or plus amiodarone on left atrial diameter (LAD) and cardiac ankyrin repeat protein(CARP) in patients with paroxysmal atrial fibrillation(PAF).[Methods] Seventy PAF patients were randomized into PNS plus amiodarone group (35 cases) and amiodarone group (35 cases). The rate of sinus rhythm maintenance, LAD and CARP were observed within 6 months of follow-up.[Results] It's demonstrated that the rate of sinus rhythm maintenance in PNS plus amiodarone group was significantly higher than that in amiodarone group (P<0.05). LAD in PNS plus amiodarone group was significantly lower than that in amiodarone group (P<0.05). CRAP in PNS plus amiodarone group was significantly lower than that in amiodarone group (P<0.05).[Conclusion] Compared to amiodarone alone, PNS plus amiodarone can significantly reduce AF recurrence, LAD and CARP in PAF patients. |
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