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Study on the rule of traditional Chinese medicine in the treatment of bile reflux gastritis in the past 5 years
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DOI   10.11656/j.issn.1672-1519.2018.08.07
Key Words   bile reflux gastritis;data mining;traditional Chinese medicine inheritance support system;prescription rule
Author NameAffiliationE-mail
LIU Xiangjin The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China  
GUO Hui The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China guohui3105@163.com 
Abstract
    [Objective] To analyze and summarize the rule of traditional Chinese medicine treatment of bile reflux gastritis based on traditional Chinese medicine inheritance support system, so as to provide reference for further excavation of traditional Chinese medicine in the treatment of bile reflux gastritis and new drug development.[Methods] Retrieval of PubMed, CNKI, Wanfang Data Knowledge Service Plat, and Weipu Database for the collection of literature on the treatment of bile reflux gastritis in the past 5 years and establishment of a prescription database.The software integration data mining method was used to distribute prescriptions according to "four odors", "five flavors" and "meridians"in the database and achieve frequency statistics,prescription regularity,correlation between drugs, core combinations and new prescription analysis.[Results] The 239 prescriptions of bile reflux gastritis were screened, and the frequency of prescription herbs was determined. The 16 new prescriptions were obtained.[Conclusion] Over the past 5 years, modern periodical literature contains bile reflux gastritis, warm medicine and cold medicine, the main flavor is bitterness and symplectic. It was mainly based on the spleen and stomach. Drug efficacy to dispersing liver-qi and regulating stomach, benefit gallbladder and removes evil heat, dispersing stagnation and resolving mass,dissipating heat and drying the damp, supplement spleen and regulating qi, mainly reflected the clinical treatment of bile reflux gastritis principle.

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