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| The clinical discussion of the methods of supplementing qi, nourishing yin and activating blood circulation to treat diabetic peripheral neuropathy |
| Hits 1363 Download times 1105 Received:April 09, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.09.05 |
| Key Words
diabetic peripheral neuropathy;methods of supplementing qi,nourishing yin and activating blood circulation;nerve conduction velocity;TCSS grade;clinical effect |
| Author Name | Affiliation | | DENG Shifang | Department of Traditional Chinese Medicine, Shenzhen People's Hospital, The Second Clinical College of Jinan University, Shenzhen 518020, China | | CHEN Wei | Department of Traditional Chinese Medicine, Shenzhen People's Hospital, The Second Clinical College of Jinan University, Shenzhen 518020, China | | BIAN Wei | Department of Traditional Chinese Medicine, Shenzhen People's Hospital, The Second Clinical College of Jinan University, Shenzhen 518020, China | | JIANG Hongyu | Department of Traditional Chinese Medicine, Shenzhen People's Hospital, The Second Clinical College of Jinan University, Shenzhen 518020, China |
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| Abstract
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| [Obejective] To observe the clinical effects of Qileng decoction via supplementing qi, nourishing yin and activating blood circulation to treat diabetic peripheral neuropathy (DPN).[Methods] A total of 90 patients with type 2 diabetes (T2DM) and PDN were enrolled in this study and randomly divided into testing group and control group, both of them received the basic therapeutic schedules including the dietary, exercise, routine blood sugar regulation and nourising peripheral neuropathy by oral mecobalamine, on that basis, the testing group took Qileng decoction additionally. All patients were treated for eight weeks, and then compared their nerve conduction velocity of median nerve and common peroneal nerve, TCSS grade of and clinical effects.[Results] Before the treatment, there was no difference of FPG, HbAlc, MCV, SCV and TCSS grades between the two groups(P>0.05). After treatment, MCV, SCV, and TCSS of the median and total peroneal nerves in the testing group and the control group were all improved compared to the pre-treatment group, and the improvement of the testing group was more obvious than that of the control group. The difference was statistically significant(P<0.05).Clinical effects were siginificant both in two groups (testing group for 93.33% and control group for 73.33%), but the testing group gained a better therapeutic effects in MCV, SCV and TCSS grades (P<0.01).[Conclusion] Qileng decoction via supplementing qi, nourishing yin and activating blood circulation to treat diabetic peripheral neuropathy could expedite the nerve conduction velocity, reducing clinical symptom and improving clinical effects. |
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