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| Distribution rule of compounds in pericarp and seed of Fructus Psoralea |
| Hits 1855 Download times 1529 Received:May 25, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.09.18 |
| Key Words
Fructus Psoralea;pericarp;seed;UPLC |
| Author Name | Affiliation | E-mail | | LI Min | Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | YANG Junjun | Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | YANG Jing | Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | WANG Yuefei | Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | CHAI Xin | Tianjin State Key Laboratory of Modern Chinese Medicine, Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | chaixinphd@aliyun.com |
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| Abstract
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| [Objective] To illuminate the distribution rule of compounds in pericarp and seed of Fructus Psoralea.[Methods] Ultra performance liquid chromatography equipped with diode array detector was employed to simultaneously determine the compounds (coumarin, flavone and monoterpene phenol) in pericarp and seed of Fructus Psoraleas.[Results] Psoralenoside and isopsoralenside were mainly distributed in seed with relative content ≥ 89.63%. Flavone and monoterpene phenol were mainly distributed in the pericarp, and the relative content of that was more than 80.86%, and corylifol C was only distributed in the pericarp. However, the coumarins such as psoralen, isopsoealen, psoralidin and 4″, 5″-dehydroisopsoralidin were distributed both in seed and pericarp, and the relative content of which was similar.[Conclusion] Psoralenoside and isopsoralenoside were found to mainly exist in seed of Fructus Psoralea. A large proportion of flavonoids and monoterpene phenolic compound were present in the pericarp of Fructus Psoralea. Coumarins with fat-solubility, such as psoralen and isopsoralen, were found in the pericarp and seed of Fructus Psoralea. |
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