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| Effect of Xiaoaiping pian combined with CT image-based interstitial brachytherapy in the treatment of elderly patients with unresectable locally advanced cervical cancer |
| Hits 1456 Download times 1207 Received:April 30, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.10.06 |
| Key Words
Xiaoaiping pian;CT image-based interstitial brachytherapy;elderly;unresectable locally advanced cervical cancer |
| Author Name | Affiliation | E-mail | | WANG Jing | Department of Gynaecology, Xi'an Gaoxin Hospital, Xi'an 710075, China | | | LIU Jing | Department of Gynaecology, Xi'an Gaoxin Hospital, Xi'an 710075, China | | | QU Hongwei | Department of Gynaecology, Xi'an Gaoxin Hospital, Xi'an 710075, China | quhongwei0390@163.com | | MU Jianning | Department of Gynaecology, Xi'an Gaoxin Hospital, Xi'an 710075, China | | | LU Zhanbin | Department of Gynaecology, Xi'an Gaoxin Hospital, Xi'an 710075, China | |
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| Abstract
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| [Objective] To evaluate the effect of Xiaoaiping pian combined with CT image-based interstitial brachytherapy in the treatment of elderly patients with unresectable locally advanced cervical cancer.[Methods] The 162 elderly patients were divided into observe group and control group, 81 cases in each group. Control group was treated by CT image-based interstitial brachytherapy, while the Xiaoaiping pian was given in observe group based the control group. After the treatment, the effects were observed. During the treatment, the adverse actions rates were observed in the two groups. Before and after the treatment, the levels of IgG, IgA, CD3+, CD4+ and CD8+ were detected in the two groups. After the treatment, the OS, PFS, 1 year, 2 years and 3 years survival rates were observed.[Results] In the evaluation of recent effect, the total effective rate was significantly higher in observe group than control group (P<0.05). After the treatment, the levels of IgG, IgA, CD3+, CD4+ and CD8+ were significantly higher in observe group than control group (P<0.05). During the treatment, the rates of abdominal pain and diarrhea, nausea and vomiting, white blood cell count reduction, platelet reduction, liver function damage, radioactive rectal damage, radioactive bladder injury and hemoglobin reduction were significantly lower in observe group than control group (P<0.05). In long-term evaluation, the OS, PFS, 1 year, 2 years and 3 years survival rates were significantly higher in observe group than control group (P<0.05).[Conclusion] Xiaoaiping pian combined with CT image-based interstitial brachytherapy in the treatment of elderly patients with unresectable locally advanced cervical cancer has a good effect, could promote the immune function, remit adverse actions and extend the survival time in patients. |
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