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| Clinical study on Xiaoyan decoction combined with Sofren injection in improving hypercoagulability of malignant tumor patients |
| Hits 1453 Download times 1158 Received:July 19, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.11.04 |
| Key Words
Xiaoyan decoction;Sofren injection;malignant tumor;hypercoagulable state;quality of life |
| Author Name | Affiliation | | ZHU Jinli | Department of Oncology, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | JIA Yingjie | Department of Oncology, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | ZHANG Shuo | The Second Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300150, China | | ZHANG Yunchao | Department of Oncology, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | LI Xiaojiang | Department of Oncology, The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | CHEN Yucheng | Graduate School, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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| Abstract
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| [Objective] To observe the clinical effect of Xiaoyan decoction combined with Sofren injection on improving hypercoagulability of malignant tumor.[Methods] Eighty cases of malignant tumor with hypercoagulable state were divided into 40 cases (Sofren injection) and 40 cases of the observation group (Xiaoyan decoction combined with Sofren injection). The two groups were treated with Sofren injection, and the combined group was given Xiaoyan decoction on the basis of the treatment. The 21 days for the 1 course of treatment, a total of 2 courses of observation. The plasma levels of prothrombin time (PT), D-two polymer (D-D2) and platelet count (PLT) were observed before and after treatment, and the changes of TCM syndrome score and KPS score were observed.[Results] Xiaoyan decoction combined with Sofren injection can reduce the level of D-D2 in blood, reduce platelet, and effectively improve the hypercoagulability state of patients. Xiaoyan decoction combined with Sofren injection group larger Rhodiola injection can improve the general symptoms of malignant tumor and improve the quality of life of patients.[Conclusion] Xiaoyan decoction combined with Sofren injection can significantly improve the hypercoagulability of malignant tumor and improve the quality of life of patients. |
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