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A randomized controlled study of type 2 diabetic gastropareses constipation by acupoint application therapy
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DOI   10.11656/j.issn.1672-1519.2018.11.09
Key Words   acupoint application therapy;type 2 diabetic gastroparesis;constipation;randomized controlled study
Author NameAffiliationE-mail
GAO Yongqian No.1 Medical Department, Miyun District Hospital of Traditional Chinese Medicine in Beijing City, Beijing 101500, China  
LU Chunqian No.1 Medical Department, Miyun District Hospital of Traditional Chinese Medicine in Beijing City, Beijing 101500, China  
LIU Fusheng Emergency Department, Dongfang Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100078, China  
LIU Jin Emergency Department, Dongzhimen Hospital Affiliated to Beijing University of Chinese Medicine, Beijing 100700, China ljhly05@163.com 
Abstract
    [Objective] To evaluate the clinical curative effect and safety of acupoint application therapy on the constipation due to type 2 diabetic gastroparesis (DGP).[Methods] The 84 patients of eligible the inclusion criteria were randomly divided into treatment group (42 cases) and control group (42 cases). Based on the control of blood glucose, the treatment group was treated by acupoint application therapy while the control group treated by oral Ma Ren Ruan Capsule (MRRC) for 4 weeks. The Constipation Symptom Integral(CSI), the Patient Assessment of Constipation Quality of Life (PAC-QOL), Glycosylated serum protein(GSP), and Security Indexes were observed before and after the treatment of both groups.[Results] The CSI (4.13±1.95) vs (8.38±1.53), PAC-QO (34.88±16.90) vs (58.18±21.65) and GSP (2.09±0.29) mmol/L vs (2.28±0.37) mmol/L of the Experimental group after treatment were better than before; The CSI (5.63±2.32) vs (8.02±2.01), PAC-QOL (45.29±19.66) vs (55.00±22.05) and GSP(2.19±0.37) mmol/L vs(2.26±0.39) mmol/L of the Control group after treatment were better than before. Both differences were statistically significant (P<0.05). After treatment, the Experimental group was better than the control group of CSI[(4.13±1.95) vs (8.38±1.53)] and PAC-QOL[(34.88±16.90) vs (45.29±19.66)], which had significant statistical difference (P<0.05); There was no statistical difference between the experimental group and the control group in GSP[(2.09±0.29) mmol/L vs (2.19±0.37) mmol/L]. No adverse events were reported in both groups.[Conclusion] It is effective and safe that the constipation due to 2 diabetic gastropareses treated by acupoint application therapy. Acupoint application therapy with traditional Chinese medicine (TCM) provide a simple and effective treatment for the constipation due to 2 diabetic gastropareses.

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