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| Study on the pharmacological effects and related mechanisms of osthole |
| Hits 1961 Download times 2009 Received:July 02, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.11.20 |
| Key Words
Fructus Cnidii;osthole;pharmacological effect;mechanism |
| Author Name | Affiliation | E-mail | | QIN Xiaoyan | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | HU Zhen | The First Affiliated Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | ZHANG Huamei | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | | MAO Haoping | Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | haoping_mao@126.com |
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| Abstract
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| Fructus Cnidii is a traditional Chinese dried and ripped fruit of Cnidium monnieri(L.), an annual herb of umbelliferae plant mainly used for external diseases in clinical settings. Recently, it has been demonstrated that the main pharmacologically active constituent of Fructus Cnidii is osthole (coumarins), popularly known as methoxyphenol. Osthole has a strong pharmacological action which has made it a powerful candidate for its effective implications in various cardiovascular, cerebrovascular, endocrine and immune system diseases. This review therefore summarizes the main pharmacological effects and related mechanisms of osthole in recent years. |
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