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| Efficacy observation and study on immune regulation on treating 40 children with infectious mononucleosis (combination of phlegm and heat syndrome) with Chaihu decocotion |
| Hits 1511 Download times 1176 Received:May 10, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.12.06 |
| Key Words
IM;Chaihu decocotion;combination of phlegm and heat syndrome;immune regulation |
| Author Name | Affiliation | | LIU Jing | Department of Pediatrics, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | CHEN Hanjiang | Department of Pediatrics, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China | | YUAN Zhiyi | Department of Pediatrics, The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China |
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| Abstract
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| [Objective] To observe the clinical effects of Chaihu decocotion in treating children with infectious mononucleosis (IM).[Methods] A total of 80 patients with children with IM from January 2014 to December 2016 in our hospital were randomly divided into treatment group and control group with 40 cases each. Both groups were given the basis of the same anti-viral treatment measures of intravenous drip ganciclovir 5 mg/kg each 12 h once,the treatment group was given Chaihu decocotion. The efficacy of the two groups were compared.[Results] The body temperature returned to normal time,angina relief, lymph node and spleen reduced, and atypical lymphocytes recovering time shortened compared with the control group(P<0.05),the CD3+ and CD8+ decreased, and the CD4+ and ratio of CD4+/CD8+ increased significantly in observation group and control group after treatment. There was no difference between EBV-DNA replication intervention and control group (P>0.05).[Conclusion] Chaihu decocotion have a good role of adjuvant therapy and shows better therapeutic effect on body immunity of children with IM, but replication of EBV-DNA intervention is invalid. |
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