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| Clinical observation of fundus laser combined with Puren Dan in treating diabetic retinopathy |
| Hits 1503 Download times 1031 Received:July 20, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2018.12.07 |
| Key Words
fundus laser;Puren Dan;diabetes;retinopathy;clinical observation |
| Author Name | Affiliation | E-mail | | WANG Haibin | Department of Ophthalmology, Affiliated Hospital of Chengde Medical University, Chengde 067000, China | | | DONG Zhijun | Department of Ophthalmology, Affiliated Hospital of Chengde Medical University, Chengde 067000, China | | | SHI Jing | Department of Ophthalmology, Affiliated Hospital of Chengde Medical University, Chengde 067000, China | | | DENG Zhihong | Department of Ophthalmology, Affiliated Hospital of Chengde Medical University, Chengde 067000, China | | | WANG Yingshuang | Department of Ophthalmology, Affiliated Hospital of Chengde Medical University, Chengde 067000, China | | | DONG Weili | Department of Ophthalmology, Affiliated Hospital of Chengde Medical University, Chengde 067000, China | wldcd@126.com |
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| Abstract
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| [Objective] Evaluation of krypton laser photocoagulation combined with traditional Chinese medicine Puren Dan on severe non proliferative diabetic retinopathy (NPDR) clinical curative effect.[Methods] Using randomized controlled methods, 70 patients with NPDR were selected, randomly divided into two groups, each group of 35 people (70 eyes). The treatment group was treated with photocoagulation combined with traditional Chinese medicine Puren Dan oral; control group received photocoagulation combined with calcium dobesilate dispersible tablets. All patients were treated for 3 months. Visual acuity, fundus fluorescein angiography, hemorrheology and traditional Chinese medicine (TCM) symptoms were observed before and after treatment.[Results] 1)The improvement of visual acuity, visual acuity of two groups before and after treatment were significantly improved, with statistical significance (P<0.05); after treatment between the two groups, the treatment group than the control group, there was significant difference between two groups (P<0.05). 2)For fundus photography, fundus fluorescein angiography, two groups before and after treatment of microaneurysm, hemorrhage, cotton wool spots were improved significantly, there was statistical significance before and after contrast (P<0.05), after treatment between the two groups was not statistically significant (P>0.05). 3)For the detection of blood rheology, treatment group and control group were improved after treatment, whole blood viscosity, erythrocyte sedimentation rate, blood viscosity decreased, and there was statistical significance (P<0.05) before and after treatment, the erythrocyte deformation index increased (F=14.1, P=0.006), the treatment group and control group before and after treatment the indexes of blood rheology were statistically significant(P<0.05). 4)The curative effect of TCM syndrome was compared between the two groups after treatment. The treatment group was obviously better than the control group. The difference was statistically significant. (P<0.05).[Conclusion] Photocoagulation combined with traditional Chinese medicine Puren Dan clinical curative effect in treatment of severe NPDR exactly. |
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