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| Multicenter clinical research to treat the acute upper respiratory tract infection in children with Reyanning Mixture |
| Hits 2143 Download times 1424 Received:November 05, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2019.02.11 |
| Key Words
Reyanning Mixture;acute upper respiratory tract infection in children;treatment;multi-center |
| Author Name | Affiliation | | WANG Hai | First Affiliated Hospital of Heilongjiang University of Chinese Medicine, Harbin 150040, China | | CHU Yajun | Tsinghua Deren Xi'an Happiness Pharmaceutical CO., LTD, Xi'an 710043, China | | LIU Yingfu | Affiliated Hospital of Jiangxi University of Traditional Chinese Medicine, Nanchang 330006, China | | TIAN Weizheng | Meishan Hospital of Traditional Chinese Medicine, Meishan 620010, China | | LIU Dexin | Liuzhou Hospital of Traditional Chinese Medicine, Liuzhou 545001, China | | ZHANG Shuangchuan | Peking University Shenzhen Hospital, Shenzhen 518034, China | | GAO Moli | Qian'an Hospital of Traditional Chinese Medicine, Qian'an 064400, China | | LI Xueming | Handan Hospital of Traditional Chinese Medicine, Handan 056000, China | | QUAN Xichun | Nanyang Hospital of Traditional Chinese Medicine, Nanyang 473002, China | | RAN Zhiling | Affiliated traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou 646000, China |
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| Abstract
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| [Objective] To observe the effect and safety of Reyanning Mixture in treating the acute upper respiratory tract infection(influenza with wind heat) in children.[Methods] The 144 cases of children who conformed to the diagnosis were randomly to divide into two groups, treatment group and control group, with 72 in each. With 4 cases eliminated in the study, and the final cases in the treatment group was 71, the control group was 69. The treatment group treated with Reyanning Mixture placebo and Shuanghuanglian Particles, and the control group treated with Shuanghuanglian Particles and Reyanning Mixture placebo. Treatment course was 5 days. To observe the time when main symptoms(fever and swollen sore throat)disappeared, fever relieving completely and the TCM syndrome efficacy, etc.[Results] Reyanning Mixture had the same efficacy as Shuanghuanglian Particles in the time when main symptoms(fever and swollen sore throat)disappeared, fever relieving completely and the TCM syndrome. The two groups was no significant difference. But the datas showed that the markedly effective rate of Reyanning Mixture in the improvement in TCM syndrome and the total effective rate in single TCM symptom(swollen sore throat, runnyopaquenose, sneeze, deep-colored urine, constipation) were highter than the Shuanghuanglian Particles.[Conclusion] Reyanning Mixture has the clinical curative effect for the acute upper respiratory tract infection in children. It is safety in use and has a good clinical application prospect. |
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