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| Effects of different fasting blood glucose levels on carotid plaque formation and the distribution characteristics of traditional Chinese medicine syndrome types in population with high risk of stroke |
| Hits 1596 Download times 1238 Received:December 30, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2019.04.10 |
| Key Words
population with high risk of stroke;fasting blood glucose;independent risk factor;carotid plaque;traditional Chinese medicine syndrome type |
| Author Name | Affiliation | E-mail | | ZHANG Xinyang | Beijing University of Chinese Medicine, Beijing 100029, China | | | CHEN Zhigang | Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100079, China | | | LIU Xuemei | Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100079, China | | | ZHANG Zhichen | Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100079, China | | | JIN Xianglan | Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100079, China | | | LIANG Xiao | Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing 100091, China | | | SHENG Xue | Wangzuozhen Community Health Service Center, Beijing 100074, China | | | YANG Xiuquan | Wangzuozhen Community Health Service Center, Beijing 100074, China | | | ZHANG Zhijun | Puhuangyu Community Health Service Center, Beijing 100075, China | | | JIA Hongyan | Fangzhuang Community Health Service Center, Beijing 100079, China | | | WU Hao | Fangzhuang Community Health Service Center, Beijing 100079, China | | | LI Aihui | Huaxiang Community Health Service Center, Beijing 100160, China | | | ZHANG Yongshun | Huaxiang Community Health Service Center, Beijing 100160, China | | | XIAO Jianbiao | Dahongmen Community Health Service Center, Beijing 100068, China | | | ZHANG Teng | Dongtieying Community Health Service Center, Beijing 100079, China | | | QI Yousheng | Dongtieying Community Health Service Center, Beijing 100079, China | | | CHEN Baoxin | Dongfang Hospital, Beijing University of Chinese Medicine, Beijing 100079, China | chenbaoxin2008@163.com |
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| Abstract
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| [Objective] To study the effects of different fasting blood glucose (FBG) levels on carotid plaque formation and the distribution characteristics of traditional Chinese medicine (TCM) syndrome types in population with high risk of stroke.[Methods] From June 2012 to March 2015,5 090 patients with diagnosis of high risk of stroke from community health service centers of Wangzuozhen,Puhuangyu,Fangzhuang,Huaxiang,Dahongmen,and Dongtieying in Beijing were selected,applied unified questionnaire,physical examination,laboratory examination,carotid artery ultrasound examination,and TCM symptoms collection. The effects on carotid plaque formationof groups with different FBG levels and the distribution characteristics of TCM Syndrome Types were analyzed.[Results] There was a significant difference shown in the result of FBG level between patients with or without carotid plaque formation (P<0.01). After adjusting other risk factors and influencing factors,impaired fasting glucose (IFG)was 1.352 times the plaque formation risk of normal fasting glucose (NFG)[95%CI(1.165,1.570),P<0.01],and diabetes mellitus (DM) was 1.552 times the plaque formation risk of NFG[95%CI=(1.328,1.814),P<0.01]. On IFG level,patients with phlegm-dampness syndrome showed a higher percentage of plaque cases than that of non-plaque cases(P<0.05),while patients with blood-stasis syndrome and internal-fire syndrome showed a higher percentage of plaque cases than that of non-plaque cases (P<0.05)on DM level.[Conclusion] IFG and DM may both be independent risk factors to carotid plaque formation. Phlegm-dampness syndrome in IFG population,blood-stasis syndrome and internal-fire syndrome in DM population might have stronger correlation with carotid plaque formation than other TCM syndromes. |
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