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Clinical research on treating type 2 diabetes mellitus with mild depression (Qiyu Huahuo symptom) by Huazhuo Jiedu modified prescription
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DOI   10.11656/j.issn.1672-1519.2019.05.10
Key Words   type 2 diabetes;depression;Huazhuo jiedu modified prescription;clinical research
Author NameAffiliation
ZHOU Jing Department of Endocrine, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
MENG Jing Baoding No.1 Hosptial of Traditional Chinese Medicine, Baoding 071000, China 
WANG Cong Department of Endocrine, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
WU Shentao Department of Endocrine, First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China 
Abstract
    [Objective] To observe the clinical effect of Huazhuo jiedu modified prescription in treating type 2 diabetes mellitus with mild depression.[Methods] According to TCM symptom scale and HAMD depression scale,64 patients with mild depression which blood glucose control well by metformin were randomly divided into two groups,32 cases in each group. On the basis of routine treatment,the control group was treated with psychotherapy,the treatment group was treated with Huazhuo Jiedu modified prescription and psychotherapy. After 12 weeks,evaluate the TCM symptom score,HAMD depression score and blood glucose of the patients before and after treatment.[Results] After treatment,the HAMD depression score of the two groups was significantly lower than that before treatment,and the effective rate of the treatment group was higher than that of the control group (P<0.05). The scores of TCM symptoms of the two groups were significantly lower after treatment than before treatment,and the curative effect of the treatment group was better than that of the control group (P<0.05). And after treatment,the decrease of blood glucose in the treatment group was higher than that in the control group(P<0.05).[Conclusion] Huazhuojiedu modified prescription has a good effect on type 2 diabetes mellitus mild depression,and there is no obvious adverse reaction.

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