|
| Effect on the depression,sleep efficiency index and the tumor marker of patients with cervical cancer by treatment combined the Kangliu Zengxiao Decoction with Ganmai Dazao Decoction |
| Hits 1469 Download times 1390 Received:February 27, 2019 |
| View Full Text View/Add Comment Download reader |
| DOI
10.11656/j.issn.1672-1519.2019.06.07 |
| Key Words
cervical cancer;traditional Chinese medicine;depression;sleep quality;tumor marker |
| Author Name | Affiliation | E-mail | | LIU Chang | Department of Oncology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China | | | ZHAO Xiaozhen | Department of Oncology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China | zhxzhtiger2001@126.com | | CAI Yuejiao | Department of Oncology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China | | | WANG Shaomo | Department of Oncology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China | | | WU Ji | Department of Oncology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China | | | XU Zhenye | Department of Oncology, Longhua Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200032, China | |
|
| Abstract
|
| [Objective] To investigate the effect on the depression,sleep efficiency index and the tumor marker of the postoperative patients or after irradiation and chemotherapy with cervical cancer by treatment combined the Kangliu Zengxiao Decoction with Ganmai Dazao Decoction.[Methods] The 186 postoperative patients or after irradiation and chemotherapy with cervical cancer were randomly divided into two groups:the Control Group (Ganmai Dazao Decoction) and the Treatment group (Kangliu Zengxiao Decoction with Ganmai Dazao Decoction). The indexes of the two groups were compared before and after intervention for three months. Hamilton Depression Scale (HAMD) score,Pittsburgh Sleep Quality Index (PSQI) score,and related tumor markers (TM),the effect of Kangliu Zengxiao Decoction with Ganmai Dazao Decoction was evaluated.[Results] The difference in HAMD scores between the treatment and the control groups was statistically significant after treatment for 3 months (P<0.05). The control group had better improvement in time for falling asleep,sleep time,sleep efficiency,sleep disorder,use of sleeping pills,and total PSQI scores before intervention. The difference was statistically significant (P<0.05); Compared with the pre-intervention,the differences in time for falling asleep,sleep time,sleep efficiency,sleep disorder,use of the sleeping pills,day function and PSQI scores were improved,and the difference was statistically significant (P<0.05). Patients in the treatment group were significantly better than the control group in terms of sleep quality,the use of hypnotic drugs,and day function,with statistically significant differences (P<0.05). Compared with ore-intervention,the levels of the CEA and SCC in the control group were significantly lower than before (P<0.05). For the treatment group,the levels of CEA,CA199,and SCC were significantly lower (P<0.05),the levels of the CEA,CA125,CA199,and SCC were all significantly lower in the treatment group than in the control group,the difference was statistically significant (P<0.05).[Conclusions] The depression level and sleep quality of the postoperative patients or after irradiation and chemotherapy with cervical cancer can comprehensively be improved by the treatment combined the Kangliu Zengxiao Decoction with Ganmai Dazao Decoction. The levels of the tumor marker were decreased,the outcome of the patients were improved. |
|
|
|
|
|
|
|
