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| Clinical efficacy study of Ruanjian Zhitong Ointment in the treatment of cancer pain |
| Hits 1429 Download times 1333 Received:December 30, 2018 |
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| DOI
10.11656/j.issn.1672-1519.2019.06.11 |
| Key Words
Ruanjian Zhitong Ointment;cancerous pain;clinical effect |
| Author Name | Affiliation | E-mail | | CHEN Liwei | The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | | ZHAO Linlin | The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | | | JIA Yingjie | The First Teaching Hospital of Tianjin University of Traditional Chinese Medicine, Tianjin 300381, China | jiayingjie1616@sina.com |
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| Abstract
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| [Objective] To observe the clinical effect of Ruanjian Zhitong Ointment in the treatment of mild to moderate cancer pain and combined with oxycodone hydrochloride controlled-release tablets in the treatment of severe cancer pain.[Methods] 1) Patients with mild to moderate cancer pain were selected and divided into two groups:Ruanjian Zhitong Ointment group and Compound Bufo Venom Ointment group. 2) Severe cancer pain patients were selected and divided into two groups:oxycodone hydrochloride controlled release tablets combined Ruanjian Zhitong Ointment group and Oxycodone Hydrochloride Controlled Release Tablets group.[Results] For patients with mild to moderate pain,there was no significant difference in remission rate between the treatment group (Ruanjian Zhitong Ointment group) and the control group (Compound Bufonis Ointment group)(P>0.05). For patients with severe pain,the treatment group (Ruanjian Zhitong Ointment combined oxycodone hydrochloride controlled release tablets group) could improve the complete remission rate of cancer pain,and the onset time,sustained remission time,average sleep time and KPS compared with the control group (oxycodone hydrochloride controlled release tablets group). The scores of HAMA and HAMD were better than those of the control group,and the difference was significant(P<0.05).[Conclusion] Ruanjian Zhitong Ointment can effectively treat mild to moderate cancer pain and is safe to use. Ruanjian Zhitong Ointment combined with oxycodone hydrochloride controlled release tablets can improve the efficacy and quality of life of patients with severe cancer pain. |
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