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| Cumulative Meta-analysis on efficacy of acupuncture therapy for restless legs syndrome |
| Hits 2182 Download times 1369 Received:January 30, 2019 |
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| DOI
10.11656/j.issn.1672-1519.2019.06.15 |
| Key Words
restless legs syndrome;acupuncture;cumulative Meta-analysis;systematic review |
| Author Name | Affiliation | E-mail | | ZHOU Rui | Clinical Medical College of Acupuncture and Moxibustion of Guangzhou Traditional Chinese Medicine University, Guangzhou 510405, China | | | LI Kesong | Guang'anmen Hospital, Chinese Academy, Traditional Chinese Medicine, Beijing 100053, China | | | ZHUANG Lixing | Clinical Medical College of Acupuncture and Moxibustion of Guangzhou Traditional Chinese Medicine University, Guangzhou 510405, China | zhuanglixing@163.com |
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| Abstract
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| [Objective] To evaluate the clinical effect of acupuncture and moxibustion on restless legs syndrome by using cumulative Meta-analysis.[Methods] Cochrane Library,PubMed,Scopus,EMbase,CNKI and other related databases were retrieved,screening studies strictly according to the inclusion and exclusion criteria. Quality evaluations and bias risk assessments were carried out for the methodology of included studies,and relevant data were extracted. Cumulative Meta-analysis was conducted by STATA 13.0,and to evaluate the grade of evidence of the outcome by Grade profiler 3.6 software.[Result] A total of 7 studies were included in the literature,which contains 419 samples. According to the cumulative Meta-analysis of the published time and sample size,the effective rate of acupuncture in the treatment of restless legs syndrome was better than that of the control group,and with the rise of the time or sample size,the cumulative effect value tended to be stable,as well as the accuracy gradually improved. The Egger test showed there was little possibility of publication bias in the included studies (P=0.597). Sensitivity analysis suggested the results were stable. The quality of outcome was low in GRADE levels of evidence.[Conclusion] The clinical efficacy of acupuncture and moxibustion in the treatment of restless legs syndrome is better than purely medicine,but we still need more high-quality,low-bias researches to further verify. |
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