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Research progress of Xuebijing Injection in the treatment of sepsis
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DOI   10.11656/j.issn.1672-1519.2019.07.05
Key Words   sepsis;Xuebijing Injection;research progress
Author NameAffiliation
LIANG Qun The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China 
GUAN Dixin The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China 
CHE Sihua Heilongjiang University of Traditional Chinese Medicine, Harbin 150040, China 
Abstract
    Sepsis is a systemic inflammatory response syndrome caused by infectious factors,the essence of which is the body's response to infectious factors. Xuebijing Injection is a Chinese patent medicine preparation developed on the basis of Xuefu Zhuyu Decoction. It is a combination of traditional Chinese medicines such as safflower,Chuanxiong,Chishao,Angelica and Salvia. Its active ingredients include ligustrazine and safflower yellow. Pigment A,Danshensu and ferulic acid have the functions of dispelling poisonous evil,promoting blood circulation and removing phlegm and clearing meridians,regulating immune response,antagonizing endotoxin and improving microcirculation disorders,and are often used in the treatment of sepsis. This article will review the pharmacological effects of Xuebijing Injection and the mechanism of action in the treatment of sepsis.

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