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| To explore the pathogenesis and TCM treatment of chronic cough based on “airway neurogenic inflammation-TRP pathway” |
| Hits 1351 Download times 1224 Received:January 16, 2019 |
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| DOI
10.11656/j.issn.1672-1519.2019.07.23 |
| Key Words
chronic cough;cough hypersensitivity;airway neurogenic inflammation;transient receptor potential channel protein;expelling wind and releasing lung;wind evil fu lung |
| Author Name | Affiliation | E-mail | | MA Jianling | Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China | | | WANG Liyun | Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China | | | JI Kun | Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China | | | LI Niuniu | Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China | | | DONG Shangjuan | Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China | | | SHI Liqing | Dongfang Hospital of Beijing University of Chinese Medicine, Beijing 100078, China | shiliqing3662@sina.com |
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| Abstract
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| Cough is common in clinic,especially for chronic cough with no obvious abnormality in chest imaging. The cause of cough is complex and it is easy to be misdiagnosed and mistreated. More attention has been paid to it,and relevant domestic and abroad guidelines have been issued. At present,cough hypersensitivity is considered as an important pathophysiological mechanism.In traditional chinese medicine,chronic cough is due to "long-term cough" category,have accumulated rich clinical experience on the etiology,pathogenesis,therapy and formulas,the author's team have focused on the disease and have done special clinical and basic researches for 15 years,according to the theory of traditional Chinese medicine and its prominent clinical symptoms put forward that "the wind evil fu lung" pathogenesis,the effect of expelling wind and releasing lung is remarkable. In this paper,combined with modern research progress of cough mechanism and previous study results,aim to discuss preliminarily the curative effect mechanism of expelling wind and releasing lung in the treatment of the disease,to enrich the scientific connotation of academic theories that wind evil fu lung pathogenesis in chronic cough,to improve the academic level of traditional Chinese medicine prevention and treatment of chronic cough. |
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