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Effect of Shuyang Huatan Fang on the efficacy and serum inflammatory factors in patients with anxiety female acne (yang depression phlegm coagulation syndrom)
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DOI   10.11656/j.issn.1672-1519.2019.08.09
Key Words   Shuyang Huatan Fang;anxiety;acne;yang depression phlegm coagulation syndrom;clinical observation
Author NameAffiliationE-mail
ZHANG Jifeng Xi'an City North Hospital Major Internal Medicine, Xi'an 710038, China  
WU Hao Department of Traditional Chinese Medicine, Air Force Medical University Tangdu Hospital, Xi'an 710038, China  
TIAN Jifeng Department of Chinese Medicine and Western Medicine, Xi'an Children's Hospital, Xi'an 710038, China  
ZHANG Hui Xi'an City North Hospital Major Internal Medicine, Xi'an 710038, China 233534808@qq.com 
Abstract
    [Objective] To observe the clinical efficacy and serum inflammatory factors in 80 female patients with anxiety and acne treated by Shuyang Huatan Decoction.[Methods] From January 2017 to January 2018,80 female acne patients with anxiety were randomly divided into treatment group and control group. The treatment group was 40 cases,the control group was 40 cases,the control group was given tanshinone Capsules orally,the treatment group was treated with Shuyang Huatan Fang on the basic treatment of the control group for 12 weeks. Efficiency,anxiety scale (SAS),dermatosis quality of life index (DLQI),serum inflammatory factors (IL-1α,IL-6,TNF-α),serum hormone level luteal hormone level (LH),estradiol (E2) and TCM Syndrome Scale adverse reactions in two groups treated before and after the treatment were observed.[Results] 1) After the treatment,the remission rate of the treatment group was 92.5%,the control group was 85.0%,and the two groups had no statistical significance(P>0.05). 2) After the treatment,the two groups had no statistical significance in acne international modified grading system score (P>0.05). 3) After the treatment,DLQI score,TCM Syndrome Scale score and anxiety scale score (SAS) had statistical significance (P<0.05). 4) Compared with the before treatment,the changes of serum inflammatory factors(IL-1α,IL-6,TNF-α),serum hormone level luteal hormone level(LH) and estradiol E2 levels in the two groups had statistical significance after the treatment(P<0.05). There was no adverse reaction before and after treatment in two groups.[Conclusion] Shuyang Huatan Fang Combined with tanshinone Capsules was effective in the treatment of anxiety female patients with acne yang depression phlegm coagulation syndrom. It is worthy of clinical application and promotion.

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