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| Observation on the clinical effect of Oseltamivir Phosphate combined with Virus Mixture in the treatment of children influenza A |
| Hits 1583 Download times 1192 Received:April 23, 2019 |
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| DOI
10.11656/j.issn.1672-1519.2019.08.10 |
| Key Words
influenza;Virus Mixture;Oseltamivir;children |
| Author Name | Affiliation | | WANG Yakun | Tianjin Children's Hospital, Tianjin 300134, China |
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| Abstract
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| [Objective] To evaluate the clinical efficacy of Virus Mixture combined with Oseltamivir Hydrochloride (Tamiflu) in the treatment of influenza A.[Methods] Sixty cases of children with influenza A treated in outpatient and emergency or hospitalization departments of Tianjin children's hospital from December 2018 to March 2019 were randomly divided into two groups,30 children in each group. The control group was treated with Tamiflu,and the experimental group was treated with the Virus Mixture developed by our hospital on the basic therapy of the control group for 5 days. The clinical efficacy,traditional Chinese medicine(TCM) syndrome score and main symptoms disappearance time before and after treatment were compared between the two groups.[Results] The total clinical effective rate of the experimental group was higher than that of the control group,and the disappearance time of fever,cough,nasal obstruction,chills,muscle and joint pain were shorter than that of the control group (P<0.05). There was no significant difference in the disappearance time of sneezing,runny nose,headache,pharyngalgia and general fatigue between the two groups (P>0.05). There was no significant difference in TCM syndrome scores between the two groups before treatment (P>0.05). After the treatment,the TCM syndrome score of the experimental group is lower than the control group,and before the treatment,the TCM syndrome score of the experimental group is higher than the control group's (P<0.05). No adverse reactions were observed in either group.[Conclusion] The clinical effect and main symptoms disappearance time of Virus Mixture combined with Tamiflu in treating influenza A were better than that of Tamiflu alone,which is worthy of clinical promotion. |
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